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Scientific CV and Publications

DNA: A, B and Z forms

Cover of book: A Century of DNA: A History of the Discovery of the Structure and Function of the Genetic Substance  by FH. Portugal and JS. Cohen, MIT Press, 1977

MRS Transverse section of human brain

Jack S. Cohen

cohen.jack@yahoo.com; cohenjk@post.bgu.ac.il

 

21 Mishol Ha’arava                                                     Department of Chemistry

Beer Sheva 84748                                                        Ben Gurion University

Israel                                                                             Beer Sheva Israel

tel: 052-888-0273 (cell)                                                   

 

Date and Place of birth:           September 6, 1938; London, U.K.

               

Education:

1958-61           Queen Mary College, London University                  B.Sc. (Chem.) 1961

1961-64           St. Catherine's College, Cambridge University          Ph.D.               1964

 

Doctoral Dissertation:             The Oxidation of Phosphites; supervised by Lord Todd

 

Experience:

1964-66           Research Fellow, Weizmann Institute, Rehovot, Israel; Science Research Council (U.K.)

1966-67           Research Fellow, Harvard Medical School, Boston, Mass.; Dept. of Pharmacology        

1967-69           Senior Research Chemist, Merck Sharpe & Dohme Research Labs, Rahway, New Jersey; Dept. of                                       Biophysics, and Pharmacology

1969-73           Senior Staff Fellow, Division of Computer Research and Technology, NIH; Physical Sciences Laboratory

1973-83           Research Chemist, National Institute of Child Health & Human Development, NIH; Located in                                             Laboratory  of Chemical Physics, National Institute of Arthritis Metabolism and Digestive Diseases, NIH

1983-90           Head, Biophysical Pharmacology Section, Clinical Pharmacology Branch, Division of Cancer Treatment;                           National Cancer Institute, NIH

1990-96           Professor, Department of Pharmacology, and Department of Biochemistry & Molecular Biology, and                                   Member, Lombardi Cancer Research Center; Georgetown University Medical Center, Washington DC

1994-96           Program Director, Molecular Biochemistry Program, National Science Foundation, Arlington VA

1996-01           Chief Scientist, Sheba Medical Center, Tel Hashomer, Israel

1996-01           Visiting Professor, Physiology & Pharmacology Department, Sackler Medical School, Tel-Aviv                                           University, Israel

2001-08           Visiting Professor, Department of Pharmacology, Faculty of Medicine, Hebrew University, Jerusalem,                                 Israel

2017-               Visiting Professor, Department of Chemistry, Ben Gurion University, Beer Sheva, Israel

                             

Service:

1990-94           Head, Experimental Therapeutics Program, Lombardi Cancer Research Center, Georgetown University                               Medical Center

1991-94           Member, Research Committee, Georgetown University Medical Center

1995-97           US Scientific Representative, Joint Expert Group for Trilateral US-Israel- Jordan Projects in Science and                             Technology

                         Served on many NIH Study Sections and site visit panels

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Other Positions:

1976-77           Foreign assignment, Department of Isotope Research, Weizmann Institute, Rehovot, Israel

1982-89           Faculty Member, Chemistry Division, Foundation for Advanced Education in the Sciences, NIH

1990-93           Chairman, Scientific Advisory Board, PharmaGenics, Inc., NJ

1992-93           Preclinical Pharmacology/Experimental Therapeutics Sub-committee of the American Association for                                 Cancer Research Program Committee

1993-96           Section for Genetic and Molecular Based Therapies, Am. Soc. for Pharmacology and Experimental                                      Therapeutics

1995-96           Lady Davis Visiting Professorship, Hebrew University, Jerusalem

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Teaching Experience:

1983-89           Developed and taught course: NMR in Biomedical Science, FAES Graduate School at NIH.

1983-89           Taught annual classes "Physical Biochemistry of DNA/Proteins," at Biochemistry Dept., GUMC

1990-95           Annual lectures in Biochemistry course on "DNA Structure and Properties"

1992                Graduate course on Advanced Molecular Pharmacology, GUMC

1993,95           Course on "Genetic Therapies" for 2nd Year Med Students (with Dr. J. Zwiebel)

1998                Course on NMR for medical students at Hadassah Medical Center

1998                Course on genetic therapy for medical students at Sackler Med School, TAU

 

Membership in Societies:

            American Chemical Society; Biophysical Society

            American Society of Biochemistry & Molecular Biology (sponsored by John Edsall,

                        and the late Christian B. Anfinsen)

            Society of Magnetic Resonance in Medicine

            American Association for Cancer Research

            American Society for Pharmacology and Experimental Therapeutics

 

Editorial Positions:

1980-02           Editorial Advisory Board, Biopolymers, Wiley-Interscience

1984-90           Editorial Board, Journal of Biochem. Biophys. Methods, Elsevier

1990-94           Editorial Board, Advances in Structural and Molecular Biology, Macmillan

1990-94           Editorial Board, Antisense Research and Development, Liebert Publishers

1990-95           Editorial Board, Anti-Cancer Drug Design, Macmillan

1993-96           Associate Editor, Cancer Gene Therapy, Appleton & Lange

1993-96           Editorial Advisory Board, Encyclopedia of Cancer, Academic Press

 

Patents:

            Patent application on deprotection of oligonucleotides (GU, 1993)

            Inhibitors for the replication of viruses and oncogenes (NIH: 5,264,423; 5,276,019, 1993)

            Metalloporphyrins as contrast agents for tumors in MRI (NIH: 4,986,256, 1991)

               

Diplomas:

            Genetics Computer Group course, GUMC, 1992

            Methods in Molecular Biology course, NIH, 1989

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